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The differences between Psilocybin and Psilocin
2 min

The differences between Psilocybin and Psilocin

Written by: Lizzy van de Berg

As curious explorers of the wondrous world of psychoactive substances, one can often get lost in a sea of information. Today, we delve into the differences between two fascinating compounds: Psilocybin and Psilocin. These names might sound familiar, especially if you're acquainted with magic mushrooms.


Let's start with Psilocybin. This is the substance commonly found in magic mushrooms. When we consume it, our body transforms psilocybin into psilocin. This process is called 'dephosphorylation' and occurs mainly in our liver. It's fascinating how a substance can transform and open the door to a world of new perceptions.


Psilocin, the active form of psilocybin, is what actually induces the psychedelic experience. It's this compound that interacts with our serotonin system, particularly the 5-HT2A receptor. It's intriguing to think that such a small chemical change can have such profound effects on our mind and perception.

The Chemical Dance

Chemically, psilocin differs from psilocybin by the absence of a phosphate group. This might seem like a minor difference, but it's crucial for how these substances function. Psilocybin is more stable and non-psychoactive until it's converted into psilocin. This makes it a perfect substance for nature to store in mushrooms.


The effects of these substances can vary. They depend on many factors, such as dosage, mood, and environment. Some experience deep spiritual journeys or intensely colorful visions, while others notice subtle shifts in thought and perception. It's a personal adventure.


It's important to emphasize that interacting with these substances should be approached with caution. They are powerful and can offer both enlightening and challenging experiences. It's crucial to prepare properly, create a safe environment, and if possible, undertake the journey with guidance from an experienced individual.


Psilocybin and Psilocin, while closely related, offer us a unique insight into the psychedelic experience. They remind us of the complexity of nature and our own minds. As we continue to deepen our understanding of these compounds, we remain in awe of their ability to transport us to unknown, yet often enlightening worlds.

Lizzy van de Berg
Meet Lizzy, an enchanting wordsmith whose exploration of the mystical world of magic mushrooms will transport you to realms both otherworldly and enlightening.